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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PDIA3
All Species:
47.27
Human Site:
Y269
Identified Species:
65
UniProt:
P30101
Number Species:
16
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P30101
NP_005304.3
505
56782
Y269
I
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Chimpanzee
Pan troglodytes
XP_001159528
485
54945
Y249
I
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Rhesus Macaque
Macaca mulatta
XP_001108948
480
54081
Y244
I
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Dog
Lupus familis
XP_535453
687
75990
Y451
V
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Cat
Felis silvestris
Mouse
Mus musculus
P27773
505
56660
Y269
T
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Rat
Rattus norvegicus
P11598
505
56605
Y269
T
A
Y
Y
D
V
D
Y
E
K
N
T
K
G
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517928
483
54617
Y246
I
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Chicken
Gallus gallus
Q8JG64
505
56163
Y267
V
A
Y
Y
D
V
D
Y
E
K
N
A
K
G
S
Frog
Xenopus laevis
NP_001080051
502
56103
Y266
I
A
Y
Y
D
V
D
Y
E
K
N
V
K
G
T
Zebra Danio
Brachydanio rerio
NP_998070
488
54656
Y260
T
A
F
F
N
V
D
Y
L
R
N
P
K
G
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P54399
496
55763
H267
F
V
S
R
E
G
G
H
I
E
K
Y
V
D
P
Honey Bee
Apis mellifera
XP_623282
490
55838
Y261
V
A
Y
Y
A
V
D
Y
I
K
N
P
K
G
T
Nematode Worm
Caenorhab. elegans
P34329
618
69779
S393
V
Y
Y
N
A
D
F
S
V
Q
Y
R
E
G
S
Sea Urchin
Strong. purpuratus
XP_782981
472
51996
Y258
T
A
Y
Y
N
V
D
Y
K
L
D
K
K
V
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P52588
513
57078
L278
A
P
K
A
M
L
F
L
N
F
S
T
G
P
F
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SRG3
508
56346
F274
K
A
M
M
F
V
N
F
T
G
A
T
A
E
A
Baker's Yeast
Sacchar. cerevisiae
P17967
522
58209
F277
L
E
E
Y
K
P
L
F
T
E
L
A
K
K
N
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
94.4
70.8
N.A.
93
92.2
N.A.
84.7
80.9
74.6
60
N.A.
32.6
49.5
36.7
50.5
Protein Similarity:
100
92.6
94.8
72.1
N.A.
97
96.2
N.A.
90.3
90.8
88.3
77.2
N.A.
53.4
63.7
50.4
65.9
P-Site Identity:
100
100
100
93.3
N.A.
93.3
86.6
N.A.
100
93.3
86.6
46.6
N.A.
0
66.6
20
46.6
P-Site Similarity:
100
100
100
100
N.A.
93.3
86.6
N.A.
100
100
93.3
80
N.A.
20
80
40
66.6
Percent
Protein Identity:
N.A.
34.3
N.A.
35.6
26.8
N.A.
Protein Similarity:
N.A.
51
N.A.
54.9
48.4
N.A.
P-Site Identity:
N.A.
0
N.A.
13.3
20
N.A.
P-Site Similarity:
N.A.
13.3
N.A.
33.3
46.6
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
6
77
0
6
12
0
0
0
0
0
6
48
6
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
53
6
71
0
0
0
6
0
0
6
0
% D
% Glu:
0
6
6
0
6
0
0
0
53
12
0
0
6
6
0
% E
% Phe:
6
0
6
6
6
0
12
12
0
6
0
0
0
0
6
% F
% Gly:
0
0
0
0
0
6
6
0
0
6
0
0
6
71
0
% G
% His:
0
0
0
0
0
0
0
6
0
0
0
0
0
0
0
% H
% Ile:
30
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% I
% Lys:
6
0
6
0
6
0
0
0
6
59
6
6
77
6
0
% K
% Leu:
6
0
0
0
0
6
6
6
6
6
6
0
0
0
0
% L
% Met:
0
0
6
6
6
0
0
0
0
0
0
0
0
0
6
% M
% Asn:
0
0
0
6
12
0
6
0
6
0
65
0
0
0
6
% N
% Pro:
0
6
0
0
0
6
0
0
0
0
0
12
0
6
6
% P
% Gln:
0
0
0
0
0
0
0
0
0
6
0
0
0
0
0
% Q
% Arg:
0
0
0
6
0
0
0
0
0
6
0
6
0
0
0
% R
% Ser:
0
0
6
0
0
0
0
6
0
0
6
0
0
0
53
% S
% Thr:
24
0
0
0
0
0
0
0
12
0
0
18
0
0
18
% T
% Val:
24
6
0
0
0
77
0
0
6
0
0
6
6
6
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
6
71
71
0
0
0
71
0
0
6
6
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _